Diego García-González, PhD
Group Leader
Institute of Biomedicine of Seville (IBiS) -
Spanish National Research Council (CSIC)
We investigate the cellular and molecular mechanisms of neurogenesis during development, and how their disruption contributes to brain disorders.
Research
Based at IBiS, our lab is dedicated to one of the most fundamental and fascinating questions in neurodevelopment: how neurogenesis generates the vast cellular diversity of the central nervous system. We investigate the molecular and cellular mechanisms underlying neural stem cell proliferation, differentiation, migration, and maturation—key processes that shape the brain’s architecture and function.
We are particularly interested in understanding how subtle deviations in these processes, occurring during critical developmental windows, can lead to long-lasting alterations in neural circuits. These disruptions are increasingly linked to psychiatric disorders such as autism, schizophrenia, and epilepsy. By using comparative neuroanatomy, single-cell transcriptomics, optogenetics, and advanced imaging techniques, we aim to uncover how neural circuits are shaped in both health and disease.
Our ultimate goal is to decipher the cellular logic of brain development, providing insights that could pave the way for new therapeutic strategies for neurodevelopmental and psychiatric disorders. Through cutting-edge experimental approaches and interdisciplinary collaborations, we work to unravel the complexity of the brain.
Main themes:
- Embryonic and postnatal neurogenesis
- Neural stem cell proliferation and differentiation
- Neuroblast migration and circuit integration
- Neurogenesis in neurodevelopmental disorders
People
Diego García-González — Principal Investigator
Elena Navarro Villarán, PhD
Isabel García Caldón, PhD student
Alejandro Pérez Recio, Master student
Antonio Alba Robles, Master student
Publications
A full list of publications is available on Google Scholar and ORCID.
Join us
We welcome applications from motivated students and postdoctoral researchers interested in neurodevelopment and neurogenesis.
Please contact dgg@csic.es with a CV and a brief statement of interest.
Additional information:
CSIC
and
IBiS
websites.
Contact
Neurogenesis & Neurodevelopmental Disorders Laboratory
Lab 113 (2nd floor)
Institute of Biomedicine of Seville (IBiS)
Avda. Manuel Siurot, s/n
41013 Seville, Spain
Follow the lab on Bluesky